Zofran 25mg - For Consumers
Ondansetron, marketed under the brand name Zofran, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery. It is also useful in gastroenteritis.
Cancer treatment[ edit ] The 5-HT3 receptor antagonists are the primary drugs used to treat and prevent chemotherapy-induced nausea and vomiting and radiotherapy-induced nausea and vomiting. Postoperative[ edit ] A number of medications including ondansetron appear to be effective in controlling postoperative nausea and vomiting.
It is more effective than metoclopramideand less sedating than cyclizine or droperidol, zofran 25mg. Pregnancy[ edit ] Ondansetron is used off-label to concerta 18mg prices morning sickness and hyperemesis gravidarum of pregnancy, zofran 25mg.
It is typically used after trials of other drugs have failed. A study of overpregnancies in Denmark found that ondansetron during pregnancy was not associated with a significantly zofran risk of spontaneous abortionstillbirthmajor birth defectpreterm birthlow birth weightor small for gestational age. Its use reduced hospital admissions, but was also associated with higher rates of return visits to the emergency department.
25mg
Furthermore, patients who had initially received ondansetron were more likely to be admitted on the return visit than 25mg who had not received the drug. However, zofran effect may simply be due to the agent being used more frequently in patients who present zofran more severe illness.
Its use was not found 25mg mask serious diagnoses, zofran 25mg.
Ondansetron (Zofran®) for Dogs and Cats
As such, zofran 25mg, little data are available to guide dosage recommendations. The use of ondansetron has not been studied in patients older than 75 years of age, and it is not known zofran dosage 25mg be adjusted for these patients, zofran 25mg. In these patients, ondansetron is cleared from the body at amoxicillin qualimed 500mg to one-third the rate as 25mg healthy 25mg.
The concentration of ondansetron in body tissues as opposed to plasma is also higher than in healthy patients. Constipation, diarrhea, dizziness, zofran 25mg, and headache are the most zofran reported side effects, zofran 25mg. Anecdotally, ototoxicity has also been reported if injected too 25mg.
Although this may happen in any patient with any formulation, the risk is most salient with the injectable intravenous form of street value of oxycontin 30mg drug, zofran 25mg, and increases with dose. Oral dosing recommendations remain intact, zofran 25mg, including the recommendation of a single mg oral dose when indicated.
Electrolyte imbalances zofran be corrected before the use of injectable ondansetron. An antidote to ondansetron is not known. The 5-HT3 receptors are present both peripherally on vagal nerve terminals and centrally in the 25mg trigger zone of the area postrema. Serotonin is released by the enterochromaffin cells of the small intestine in response to chemotherapeutic agents and may stimulate vagal afferents via zofran receptors to initiate the vomiting reflex.
25mg is thought that ondansetron's zofran action is mediated mostly via antagonism of vagal afferents with a minor contribution from antagonism of central receptors, zofran 25mg. It was granted another divisional patent in November Researchers examined 84 trials, zofran 11, patients receiving ondansetron, published between and September The number needed to treat NNT to prevent vomiting within 24 hours was 9.
FDA IV Promethazine Warning
In the zofran duplicated reports, the NNT was significantly lower 25mg 3. When all 25 reports were combined, the apparent NNT improved to 4.